Recombinant Human Heat Shock Protein 90kDa Beta (GRP94) Member 1, HEK
Catalogue Number: 32-5333-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Alias: | ECGP||GP96||TRA1||GRP94||HSP90B1||Endoplasmin||Heat shock protein 90 kDa beta member 1||94 kDa glucose-regulated protein||gp96 homolog||Tumor rejection antigen 1. |
| Shipping Condition: | Dry Ice |
| Unit(s): | 10 ug |
Description
Description: Source : HEK 293. HSP90B1 Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (Asp22-Glu798) containing a total of 789 amino acids, having a calculated molecular mass of 90.9kDa. HSP90B1 is fused to a 2 aa N-terminal linker, a 4 aa C-terminal linker and a 6 aa His tag at C-Terminus. HSP90B1 is an abundant molecular chaperone resident endoplasmic reticulum (ER) lumenal stress protein which is part of the Hsp90 family. HSP90B1 is involved in maintaining protein homeostasis in the secretory pathway as well as functioning in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. HSP90B1 has key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90B1 protein associates with numerous cochaperones and involved in folding of newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is highly expressed in human gastric carcinoma BGC-823 cells during the whole cell cycle.
Additional Text
Application Notes
It is recommended to add 200µl deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. HSP90B1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
32-5333 Datasheet
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