Recombinant Human GM-CSF/CSF2 (P. pastoris)
Catalogue Number: 32-7033-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Shipping Condition: | RT |
| Unit(s): | 10 ug, 50 ug |
Description
Description: Source: P.Pichia. MW :14.4kD. Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is produced by our Yeast expression system and the target gene encoding Ala18-Glu144 is expressed. GM-CSF was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/macrophages, and eosinophils, GM-CSF has also been reported to have a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines.
Additional Text
Gene Name
CSF2
Gene ID
1437
Uniprot ID
P04141
Application Notes
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test. Biological Activity : ED50 is less than 0.2 ng/ml. Specific Activity of 5.0 x 10^6 IU/ mg.
32-7033 Datasheet
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