Recombinant Rat VEGF-A/VEGF164
Catalogue Number: 32-8567-ABO
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Shipping Condition: | RT |
| Unit(s): | 10 ug, 50 ug |
Description
Description: Source: P.Pichia. MW :19.2kD. Recombinant Rat Vascular Endothelial Growth Factor A is produced by our Yeast expression system and the target gene encoding Ala27-Arg190 is expressed. Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic , paraventricular nuclei and the choroid plexus of the pituitary, and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide, and alternative splicing of rat VEGF gene produces isoforms of 120, 144, 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and play important roles in inducing endothelial cell proliferation, promoting cell migration, inhibiting apoptosis and inducing permeabilization of blood vessels.
Additional Text
Gene Name
VEGFA
Gene ID
83785
Uniprot ID
P16612
Application Notes
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
32-8567 Datasheet
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