Polyclonal Antibody to NFkB-p105/p50(Phospho-Ser893)
Catalogue Number: 35-1017-ABO
35-1017 Image
35-1017 Image
35-1017 Image
Figure 1: Immunofluorescence staining of methanol-fixed HeLa cells using NFkB p105 (phospho-Ser893) antibody (35-1017 Red).
35-1017 Image
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFkB p105 (phospho-Ser893) antibody (35-1017 ).
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | KBF1|| NF-kB1|| NFkappaB |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around aa.891~895 (A-S-S-P-V) derived from Human NFkB-p105. |
| Application: | IF, IHC |
Description
Description: NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Additional Text
Gene Name
NFKB1
Gene ID
4790
Uniprot ID
P19838
Antibody Clonality
Polyclonal
Application Notes
Immunohistochemistry 1:50~1:100 Immunofluorescence 1:100~1:200
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