Catalogue Number: 35-1215-ABO
Manufacturer: | Abeomics |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | IRS-1|| IRS1 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 50 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Peptide sequence around phosphorylation site of serine 636 (P-M-S(p)-P-K) derived from Human IRS-1. |
Application: | WB, IHC |
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
IRS1
3667
P35568
Polyclonal
Predicted MW: 180kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100