Polyclonal Antibody to IRS-1 (Phospho-Ser639)
Catalogue Number: 35-1216-ABO
35-1216 Image
35-1216 Image
35-1216 Image
Figure 1: Western blot analysis of extracts from 293 cells untreated or treated with serum using IRS-1(Phospho-Ser639) Antibody 35-1216 .
35-1216 Image
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1(Phospho-Ser639) Antibody 35-1216 (left) or the same antibody preincubated with blocking peptide(right).
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | IRS-1|| IRS1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around phosphorylation site of serine 639 (P-K-S(p)-V-S) derived from Human IRS-1. |
| Application: | WB, IHC |
Description
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
Additional Text
Gene Name
IRS1
Gene ID
3667
Uniprot ID
P35568
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 180kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
35-1216 Datasheet
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