Polyclonal Antibody to Histone H3 (Di-Methyl-Lys27)

Catalogue Number: 35-1348-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:H3/a||H3/c||H3/d||H3/f||H3/h
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around Di-Methylation site of ysine 27(A-R-K(di-methyl)-S-A) derived from Human Histone H3.
Application: WB, IHC

Description

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, imiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Additional Text

Gene ID

8350

Uniprot ID

P68431

Antibody Clonality

Polyclonal

Gene Name

H3C1

Application Notes

Predicted MW: 17kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100