Catalogue Number: 35-1373-ABO
Manufacturer: | Abeomics |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | DNA-binding factor KBF2|| H2TF1|| ymphocyte translocation chromosome 10|| yt10|| NFKB2 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 50 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Peptide sequence around aa.868~872 (Y-G-S-Q-S) derived from Human NFkB-p100. |
Application: | WB, IHC |
Description: NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been inked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, ung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been inked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. Qu Z, et al. (2004) J Biol Chem; 279(43): 44563-72. Xiao G, et al. (2001) J Biol Chem 7(2): 401-9.
Polyclonal
Predicted MW: 120 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100