Polyclonal Antibody to HDAC4 (Ab-632)

Catalogue Number: 35-1489-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:HD4|| Histone deacetylase 4
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around aa. 630~634 (A-Q-S-S-P) derived from Human HDAC4.
Application: IF, WB

Description

Description: Responsible for the deacetylation of ysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of arge multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Additional Text

Gene ID

9759

Gene Name

HDAC4

Uniprot ID

P56524

Antibody Clonality

Polyclonal

Application Notes

Predicted MW: 140kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200