Polyclonal Antibody to NFkB-p100/p52 (Ab-872)
Catalogue Number: 35-1625-ABO
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35-1625 Image
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Figure 1: Western blot analysis of extracts from HT29 cells using NFkB-p100(Ab-872) Antibody 35-1625 and the same antibody preincubated with blocking peptide.
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Figure 2: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using NFkB-p100/p52(Ab-872) Antibody 35-1625 (left) or the same antibody preincubated with blocking peptide(right).
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Figure 3: Immunofluorescence staining of methanol-fixed Hela cells using NFkB-p100(Ab-872) Antibody 35-1625 .
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | DNA-binding factor KBF2|| H2TF1|| ymphocyte translocation chromosome 10|| yt10|| NFKB2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around aa.870~874 (S-Q-S-V-E) derived from Human NFkB-p100. |
| Application: | IF, WB, IHC |
Description
Description: NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. Shin HM, et al. (2006) EMBO J; 25(1): 129-138. Li Q, et al. (2005) Proc Natl Acad Sci USA; 102(35): 12425-12430. Chen C, et al. (2000) Mol Cell Biol; 20(8): 2687-2695.
Additional Text
Gene Name
NFKB2
Gene ID
4791
Uniprot ID
Q00653
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 120 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
35-1625 Datasheet
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