TNF alpha (Tumor Necrosis Factor Superfamily Member 2, TNFSF2, TNFA)

Catalogue Number: 361672-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2, 0.02% Proclin-300.
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	APC1 protein\|cachectin\|DIF\|TNF, macrophage-derived\|TNF, monocyte-derived\|TNFA\|TNF-a\|TNF-alpha\|TNFSF2\|TNLG1F\|tumor necrosis factor\|tumor necrosis factor ligand 1F\|tumor necrosis factor ligand superfamily member 2\|tumor necrosis factor-alpha
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Human
Clone:	CDP 571 (Humicade) (recomb)
Isotype:	IgG4, kappa
Immunogen:	Human TNF-alpha
Application:	ELISA, NT

Overview
Datasheets

Description

Description: Recombinant monoclonal antibody toTNF alpha with variable regions (i.e. specificity) from the hybridoma CDP 571 (Humicade). Manufactured using a proprietary recombinant platform technology. Not for therapeutic use; this is a research grade biosimilar. TNF-alpha is a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Specificity

Recognizes human TNF-alpha.

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

361672 Datasheet

Price

£846.00

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