5-Hydroxymethylcytosine (5hmc)
Catalogue Number: 375997-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rat |
| Clone: | AB3/63.3 |
| Isotype: | IgG2a, kappa |
| Immunogen: | 5-Hydroxymethylcytosine conjugated to BSA. |
| Application: | IF, IP, DB |
Description
Description: The 5-Hydroxymethylcytosine antibody, detects 5-hydroxymethyl cytosine (hmc, 5hmc), but not 5-methylcytosine or unmethylated cytosine. 5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. Every mammalian cell contains 5-hydroxymethylcytosine, but the levels vary depending on the cell type, generally, the levels of 5-hydroxymethylcytosine increase with age. Although the exact function has not been fully elucidated, studies suggest that 5-hydroxymethylcytosine may regulate gene expression or initiate DNA demethylation.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
375997 Datasheet
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