Catalogue Number: 39-1004-ABO
Manufacturer: | Abeomics |
Shelf Life: | 12 months |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Apoptosis regulator Bcl-2; Bcl2; Bcl-2 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug |
Host name: | Mouse |
Clone: | Bcl-2-100 |
Isotype: | IgG1 |
Immunogen: | Synthetic peptide corresponding to residues 41-54 of the bcl-2 protein, conjugated to thyroglobulin. |
Application: | ICC, IHC-P, WB, IHC-Fr |
Description: Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t(14;18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene. Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.
BCL2
24224
P49950
Monoclonal
Western blot : 1-2µg/ml; Immunohistochemistry(Paraffin-embedded Section) : 0.4-1µg/ml; Immunohistochemistry(Frozen Section) : 0.4-1µg/ml; Immunocytochemistry : 1µg/ml