Anti-FOXP3 Polyclonal Antibody

Catalogue Number: 39-2001-ABO

Manufacturer:Abeomics
Shelf Life:12 months
Physical state:Lyophilized
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Forkhead box protein P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; FOXP3; IPEX; JM2
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: E.coli-derived Human FOXP3 recombinant protein (Position: H101-P431). Human FOXP3 shares 88% amino acid (aa) sequence identity with Mouse FOXP3.
Application: IHC-P

Description

Description: FOXP3(forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Additional Text

Gene Name

FOXP3

Gene ID

50943

Uniprot ID

Q9BZS1

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Application Notes

Immunohistochemistry(Paraffin-embedded Section) : 0.5-1µg/ml