Catalogue Number: 39-2001-ABO
Manufacturer: | Abeomics |
Shelf Life: | 12 months |
Physical state: | Lyophilized |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | Forkhead box protein P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; FOXP3; IPEX; JM2 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | E.coli-derived Human FOXP3 recombinant protein (Position: H101-P431). Human FOXP3 shares 88% amino acid (aa) sequence identity with Mouse FOXP3. |
Application: | IHC-P |
Description: FOXP3(forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.
FOXP3
50943
Q9BZS1
Affinity Purified
Polyclonal
Immunohistochemistry(Paraffin-embedded Section) : 0.5-1µg/ml