Anti-MBD2 Polyclonal Antibody
Catalogue Number: 39-2005-ABO
39-2005 Image
39-2005 Image
39-2005 Image
Figure 1: Anti-MBD2 antibody (39-2005). Western blotting: Lanes: Anti MBD2 (39-2005) at 0.5µg/ml. WB: Recombinant Human MBD2 Protein 0.5ng. Predicted band size: 40 kDa. Observed band size: 40 kDa.
39-2005 Image
Figure 2: Anti-MBD2 antibody (39-2005). Western blotting: Lanes: Anti MBD2(39-2005) at 0.5µg/ml, Lane 1: SGC Whole Cell Lysate at 40ug, Lane 2: HELA Whole Cell Lysate at 40ug, Lane 3: JURKAT Whole Cell Lysate at 40ug, Lane 4: K562 Whole Cell Lysate at 40ug. Predicted band size: 47 kDa: Observed band size: 47 kDa.
| Manufacturer: | Abeomics |
| Shelf Life: | 12 months |
| Physical state: | Lyophilized |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Methyl-CpG-binding domain protein 2; Demethylase; DMTase; Methyl-CpG-binding protein MBD2; MBD2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | E.coli-derived human MBD2 recombinant protein (Position: W159-A411). Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2. |
| Application: | WB |
Description
Description: Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
Additional Text
Gene Name
MBD2
Uniprot ID
Q9UBB5
Purification
Affinity Purified
Gene ID
8932
Antibody Clonality
Polyclonal
Application Notes
Western blot : 0.1-0.5µg/ml
39-2005 MSDS
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