CD27 (SWC2, Swine Workshop Cluster 2) (APC)

Catalogue Number: 397010-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: B30C7
Isotype: IgG1
Immunogen: Porcine peripheral blood monocytes.
Application: FC

Description

Description: In humans the CD27 antigen is expressed by discrete populations of T- and B-cells where it functions in a co-stimulatory role to induce proliferation of T-cells and B-cells, however studies undertaken using the CD27 have been unable to detect expression of CD27 on porcine B-cells. Studies in humans have demonstrated CD27 to be involved in apoptosis, research in swine has shown that porcine CD27 is expressed by all naive CD8a-ve T-helper cells and a sub-population of CD8a+ve cells. Monoclonal antibodies to CD27 have previously been used to differentiate between subsets of NK cells and research utilizing CD27 has shown that this monoclonal antibody may be used to differentiate between subsets of porcine NK cells.

Additional Text

Gene Name

CD27

Gene ID

100520023

Purification

Protein A purified

Uniprot ID

F1SL30

Antibody Clonality

Monoclonal