CSF1R (CD115, CSF-1R) (APC)

Catalogue Number: 397046-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: ROS8G11
Isotype: IgG2a
Immunogen: Recombinant fusion protein corresponding to porcine CSF1R.
Application: FC

Description

Description: CSF1R (CD115) is a single pass type 1 transmembrane protein belonging to the type III protein kinase family and is the cell surface receptor for both CSF1 and IL-34. Evidence from comparative sequence analysis across a range of vertebrate species indicates that CSF1 and IL-34 interact with distinct regions of CSF1R. CSF1R cell surface expression appears to be one of the earliest events in macrophage lineage cell commitment and CSF1R expression appears primarily limited to macrophages. The development of the monoclonal antibody specifically recognizing porcine CSF1R provides an antibody that will assist with research into porcine monocyte and macrophage biology.

Additional Text

Purification

Protein A purified

Antibody Clonality

Monoclonal