C-reactive Protein (Equine) ELISA, 96 wells,"RUO"
Catalogue Number: 41-CRPEQ-E01-ALP
| Manufacturer: | Alpco Diagnostics |
| Type: | Horse ELISA Kit |
| Shipping Condition: | RT |
| Unit(s): | 96 Wells |
| Range: | 10-320 ng/mL |
| Sensitivity: | 10 ng/ml |
| Sample type: | Plasma |
| Sample size: | 5 µL |
| Application: | ELISA, IA |
Description
Description: The Equine C-reactive Protein ELISA (Equine CRP ELISA) is a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring CRP in horse biological samples. Acute phase proteins are plasma proteins which increase in concentration following infection, inflammation or trauma. The first acute phase protein to be recognized was discovered in humans by Tillet and Frances in 1930(1). This C-reactive protein (CRP) is so named because it is able to effect precipitation of somatic C-polysaccharide of Streptococcus pneumonia. CRP is an alpha globulin with a mass of 110 - 140 kD, and is composed of five identical subunits, which are non-covalently assembled as a cyclic pentamer. It is synthesized in the liver and, in humans, is normally present as a trace constituent of serum at levels less that 0.3 mg/dL. The levels in serum rise quickly following acute tissue damage and also falls very rapidly once the stimulus is removed. It has been proposed that the function of CRP is to aid in complement activation, influence phagocytic cell function, and augment cell mediated cytotoxicity. Investigations over the past few years have shown that quantification of these in plasma or serum can provide valuable diagnostic information in the detection, prognosis, and monitoring of disease not only in humans, but in companion animals and farm herds as well(2). (1) Tillett et al (1930) J Exp Med 52:561-71. (2) Eckersal (2000) Revue Med Vet 151(7): 577-84. The Equine C-reactive Protein ELISA (Equine CRP ELISA) is for Research Use Only. For more information on the Equine C-reactive Protein ELISA (Equine CRP ELISA), call 800-592-5726.
Additional Text
Regulatory Statuses
Research Use Only. Not for Use in Diagnostic Procedures.
Short Description
Equine C-reactive Protein ELISA (Equine CRP ELISA)
41-CRPEQ-E01 Protocol
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