C-reactive Protein (Feline) ELISA, 96 wells,"RUO"
Catalogue Number: 41-CRPFE-E01-ALP
| Manufacturer: | Alpco Diagnostics |
| Type: | Feline ELISA Kit |
| Shipping Condition: | RT |
| Unit(s): | 96 Wells |
| Range: | 3.125 - 200 ng/mL |
| Sensitivity: | 3.125 ng/mL |
| Sample type: | Plasma |
| Sample size: | 5 µL |
| Application: | ELISA, IA |
Description
Description: The Feline C-Reactive Protein ELISA (Feline CRP ELISA) is a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring CRP in feline biological samples. The Feline C-Reactive Protein ELISA (Feline CRP ELISA) is for Research Use Only. Acute phase proteins are plasma proteins which increase in concentration following infection, inflammation or trauma. The first acute phase protein to be recognized was discovered in humans by Tillet and Frances in 1930(1). This C-reactive protein (CRP) is so named because it is able to effect precipitation of somatic C-polysaccharide of Streptococcus pneumonia. CRP is an alpha globulin with a mass of 110 - 140 kD, and is composed of five identical subunits, which are non-covalently assembled as a cyclic pentamer. It is synthesized in the liver and, in humans, is normally present as a trace constituent of serum at levels less that 0.3 mg/dL. The levels in serum rise quickly following acute tissue damage and also falls very rapidly once the stimulus is removed. It has been proposed that the function of CRP is to aid in complement activation, influence phagocytic cell function, and augment cell mediated cytotoxicity. Investigations over the past few years have shown that quantification of these in plasma or serum can provide valuable diagnostic information in the detection, prognosis, and monitoring of disease not only in humans, but in companion animals and farm herds as well(2). (1) Tillett et al (1930) J. Exp Med. 52:561-71. (2) Eckersal (2000) Revue Med. Vet. 151(7): 577-84. For more information on the Feline C-Reactive Protein ELISA (Feline CRP ELISA), call 800-592-5726.
Additional Text
Regulatory Statuses
Research Use Only. Not for Use in Diagnostic Procedures.
Short Description
Feline C-Reactive Protein ELISA (Feline CRP ELISA)
41-CRPFE-E01 Protocol
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