Mouse Monoclonal Antibody to Ipilimumab (Clone : 26B6H7D9)

Catalogue Number: 45-1091-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 40 ug
Host name: Mouse
Clone: 26B6H7D9
Isotype: IgG1
Immunogen: Ipilimumab
Application: ELISA

Description

Description: Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells Anti-Ipilimumab Antibody (26B6H7D9), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Ipilimumab.

Additional Text

Purification

Protein A purified

Antibody Clonality

Monoclonal

Application Notes

ELISA detection: 0.01-0.1 µg/ml