CRF-HS, Mouse/Rat EIA, "RUO"
Catalogue Number: 48-CRFMS-E01-ALP
| Manufacturer: | Alpco Diagnostics |
| Type: | Rodent ELISA kit |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 96 Wells |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Range: | 0.078 - 2.5 ng/mL |
| Sensitivity: | 0.078 ng/mL |
| Sample type: | Cell Culture, Plasma |
| Sample size: | 50 µL |
| Application: | IA, EIA |
Description
Description: Corticotropin releasing factor (CRF, also CRH) was initially isolated from ovine hypothalamus by Vale et al., in 1981, and identified as a novel neuropeptide comprising 41 amino acid residues with molecular weight 4758 (1). Later human CRF (2) and rat CRF (3) were also isolated and identified. The mouse CRF peptide is identical at amino acid level to the rat and human CRF peptides (4). CRF in anterior pituitary promotes the synthesis and secretion of ACTH, a main factor of hypothalamus-pituitary-adrenal (HPA) axis. In the rat and human, CRF distributes mainly in the hypothalamus, but it was also found in the spinal cord, stomach, spleen, duodenum, adrenal, and placenta. In addition, immunochemical evidence supported the wide distribution of the peptide throughout the central nervous system (CNS) such as olfactory bulb, retina and central auditory system in the rat. Please see Instructions for Use for references.
Additional Text
Regulatory Statuses
Research Use Only. Not for Use in Diagnostic Procedures.
Short Description
Mouse / Rat CRF-HS ELISA (Mouse / Rat High Sensitivity Corticotropin Releasing Factor ELISA)
Storage Note
store at 2-8C
48-CRFMS-E01 Protocol
SUPPORT
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PRODUCT
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DELIVERY
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