CD56 (CD56 Antigen, Cell Adhesion Molecule Neural 1, MSK39, Neural Cell Adhesion Molecule 1, NCAM 1, NCAM1, NCAM-1, NCAM) (APC)

Catalogue Number: 516437-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-188
Isotype: IgG2a
Immunogen: KG-1 human acute myelogenous leukemia cell line
Application: FC

Description

Description: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120kD, 140kD or 180kD isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors.

Additional Text

Gene Name

NCAM1

Gene ID

4684

Uniprot ID

P13591

Purification

Purified

Antibody Clonality

Monoclonal