CD80 (APC)
Catalogue Number: 516476-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | activation B7-1 antigen|B7 protein|B71|Cd28l|Ly53|Ly-53|MIC17|T-lymphocyte activation antigen CD80|TSA1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Hamster |
| Clone: | 16-10A1 |
| Isotype: | IgG |
| Immunogen: | CHO cell line transfected with mouse B7 (CD80). Species Sequence Homology: canine |
| Application: | FC |
Description
Description: CD80 is a 60kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Additional Text
Gene Name
CD80
Gene ID
12519
Purification
Affinity Purified
Uniprot ID
Q00609
Antibody Clonality
Monoclonal
516476 Datasheet
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