Pembrolizumab Biosimilar, Human PD-1
Catalogue Number: 587286-USB
| Manufacturer: | United States Biological |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 5 mg |
| Host name: | Human |
| Clone: | |
| Isotype: | IgG4, kappa |
| Immunogen: | Recombinant human PD1 produced in the pembrolizumab biosimilar CHO stable cell line. |
| Application: | ELISA, NT |
Description
Description: Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptor. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype with the containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds. Pembrolizumab Biosimilar uses the same protein sequences as the therapeutic antibody pembrolizumab.
Additional Text
Antibody Clonality
Recombinant Monoclonal
587286 Datasheet
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