Bassoon

Catalogue Number: 589968-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: SAP7F407
Isotype: IgG2a, kappa
Immunogen: Recombinant protein corresponding to rat Bassoon.
Application: ICC, IF, IP, WB, IHC

Description

Description: Bassoon is a 420kD protein that localizes at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to colocalize with GABA (A) and glutamate (GluR1) receptors. These observations suggested that they serve specific functions at synaptic junctions and may be involved in organization of the cytoskeleton at the site of neurotransmitter release.

Additional Text

Purification

Protein G purified

Uniprot ID

O88778

Antibody Clonality

Monoclonal