XBP-1S
Catalogue Number: 590542-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 8F6.11 |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to human XBP-1, spliced isoform XBP1(S) at C-terminal. |
| Application: | ELISA, ICC, IP, WB |
Description
Description: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of misfolded proteins in the endoplasmic reticulum (ER). XBP-1 mRNA is spliced by IRE1p under ER stress, resulting in a 371aa protein (XBP-1s) which is translocated to the nucleus where it binds to the regulatory elements of downstream genes. XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones grp78 and grp94.
Additional Text
Uniprot ID
P17861
Gene ID
7494
Purification
Protein G purified
Gene Name
XBP1
Antibody Clonality
Monoclonal
590542 Datasheet
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