6-OG488 succinimidyl ester [equivalent to Oregon Green® 488 carboxylic acid, succinimidyl ester, 6-isomer ]

Catalogue Number: 711-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Fluorophores
Shipping Condition:RT
Unit(s): 5 mg

Description

Description: 6-OG488 succinimidyl ester is the same molecule to Oregon Green® 488 carboxylic acid, succinimidyl ester, 6-isomer (Invitrogen #O6185, Oregon Green® is the Trademark of Invitrogen). This fluorinated analog of fluorescein has higher photostability and a lower pKa ~ 4.7 while 6-FAM has pKa ~6.4. The decreased pKa of 6-OG488 makes its fluorescence essentially pH insensitive in the physiological pH range. This amine-reactive 6-OG488 succinimidyl ester can be used to make bright green fluorescent bioconjugates with excitation/emission maxima ~496/524 nm. It is an excellent replacement to 6-FITC that has severe pH dependence and low photostability.

Additional Text

Storage Note

Freeze (< -15 °C); Minimize light exposure;|12 months