Prostacyclin ELISA (Urine), 5x96 Wells, "RUO"
Catalogue Number: 74-PCNHU-E05-URN-ALP
| Manufacturer: | Alpco Diagnostics |
| Type: | Human ELISA Kit |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 5 x 96 Wells |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Range: | 7.81 - 2,000 pg/mL |
| Sensitivity: | 6.58 pg/mL |
| Sample type: | Cell Culture, Urine |
| Sample size: | |
| Application: | ELISA, IA |
Description
Description: Prostacyclin (PGI2) is involved in platelet aggregation, vasoconstriction, and reproductive functions (1-3). PGI2 has a half life of 60 minutes in plasma but only 2 to 3 minutes in buffer (3). The production of PGI2 is typically monitored by measurement of 6k-PGF1α and 2,3d-6k-PGF1α. 6-keto-PGF1α is produced by the non-enzymatic hydration of PGI2, and is further metabolized in urine to the 2,3-dinor derivative. A number of pharmaceuticals alter and/or inhibit the synthesis of PGI2 (4). Methods to measure PGI2 in urine typically involve HPLC5 , gas chromatography/mass spectrometry (6), or radioimmunoassay (7,8) and enzyme immunoassay (9) for 6k-PGF1α. Please see instructions for use for references.
Additional Text
Regulatory Statuses
Research Use Only. Not for Use in Diagnostic Procedures.
Short Description
Prostacyclin ELISA (Urine)
Storage Note
store at 2-8C
74-PCNHU-E05-URN Protocol
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