TXB2 ELISA, 5x96 wells, "RUO"

Catalogue Number: 74-TXBHU-E05-ALP

Manufacturer:Alpco Diagnostics
Type:Human ELISA Kit
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 5 x 96 Wells
Host name:
Clone:
Isotype:
Immunogen:
Range: 13.7 - 10,000 pg/mL
Sensitivity: 10.54 pg/mL
Sample type: Cell Culture, Plasma, Saliva, Serum, Urine
Sample size:
Application: ELISA, IA

Description

Description: Thromboxane A2 (TXA2) is involved in platelet aggregation, vasoconstriction, and reproductive functions (3-5). However, TXA2 has a half-life of only 37 seconds under physiological conditions (5), and the production of TXA2 in vivo is typically monitored by measurement of TXB2 and 2,3-dinor TXB2. Thromboxane B2 (TXB2) is produced by the non-enzymatic hydration of TXA2, and has been shown to be stable (6,7). A number of pharmaceuticals alter and/or inhibit the synthesis of TXA2 (8-10) and methods to determine TXA2 in urine and blood typically involve gas chromatography/mass spectrometry11, radioimmunoassay, or enzyme-linked immunoassay. See instructions for use for references.

Additional Text

Regulatory Statuses

Research Use Only. Not for Use in Diagnostic Procedures.

Short Description

For the quantitative determination of TXB2 in culture supernatants, plasma, serum, saliva, and urine from any species. Cited sample types include cell lysate1, coronary effluent2, liver perfusate3, platelets4, rectal dialysate5, and whole blood6. 1. Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase: H.B. Suliman, et al. ; Am. J. Physiol. Lung Cell Mol. Physiol. 280, L69 (2001) 2. Sevoflurane and Isoflurane Do Not Enhance the Pre- and Postischem

Storage Note

store at 2-8C

Price
£1,981.00


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