Chymotrypsin
Catalogue Number: A-2005-1-RPE
| Manufacturer: | rPeptide |
| Physical state: | Salt-free lyophilized solid |
| Type: | Proteases |
| Shipping Condition: | RT |
| Unit(s): | 100 ug |
Description
Description: Chymotrypsin-like proteasome activities were found to increase in cells treated with 10-100 uM 6-OHDA, while "higher doses caused a marked decline" Such harsh oxidative attacks might cause failure of the ubiquitin-proteasome system (UPS) which leads to protein aggregation and cell death. "Mutations in familial PD have been associated with the failure of protein degradation through UPS".
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