ABC A1 (ATP-binding Cassette (ABC) Tansporter 1) (MaxLight 650)
Catalogue Number: A0004-01-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | ABC1|ABC-1|ATP-binding cassette sub-family A member 1|ATP-binding cassette transporter A1|ATP-binding cassette, sub-family A (ABC1), member 1|CERP|cholesterol efflux regulatory protein|HDLDT1|membrane-bound|TGD |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 7i4 (AB.H10) |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to aa1800-2260 from human ABC A1 |
| Application: | IP, WB, IHC, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo- endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Additional Text
Gene Name
ABCA1
Gene ID
19
Specificity
Recognizes human ABCA1. Species Crossreactivity: mouse and chicken.
Purification
Purified
Uniprot ID
O95477
Accession Number
NM_005502.2
Antibody Clonality
Monoclonal
A0004-01-ML650 Datasheet
SUPPORT
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