ABCA1 (ABC 1, ABC Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, HDLDT1, TGD) (MaxLight 490)
Catalogue Number: A0004-01A-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Abc1|ABC-1|ATP-binding cassette 1|ATP-binding cassette sub-family A member 1|ATP-binding cassette transporter 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 5A1-1422 |
| Isotype: | IgG2a |
| Immunogen: | ABCA1 transfected HeLa cells. |
| Application: | FC, IF |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABCA subfamily, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.
Additional Text
Gene Name
ABCA1
UniProt ID
P41233
Specificity
Recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1).
Purification
Protein G purified
Gene ID
11303
Antibody Clonality
Monoclonal
A0004-01A-ML490 Datasheet
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