ACTH, CT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin) (HRP)
Catalogue Number: A0758-06-HRP-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2Q2137 (56) |
| Isotype: | IgG1 |
| Immunogen: | ACTH, conjugated to BSA. Epitope: C-terminus. |
| Application: | ELISA, ICC, IHC |
Description
Description: Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease.
Additional Text
Gene Name
POMC
Gene ID
5443
Specificity
Recognizes human CLIP (17-39 ACTH). No crossreaction with Synacthen (1-24 ACTH). Species Crossreactivity: rat C-terminal ACTH.
Uniprot ID
P01189
Purification
Protein A purified
Antibody Clonality
Monoclonal
A0758-06-HRP Datasheet
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