Adenylate Kinase 1 (Adenylate Kinase Isoenzyme 1, AK 1, AK1, AK-1, Adenylate Kinase Soluble, ATP-AMP Transphosphorylase, Myokinase) (MaxLight 650)
Catalogue Number: A0882-65C-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3A6-1F5 |
| Isotype: | IgG1, kappa |
| Immunogen: | AK1 (AAH01116, 1-195aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26kD. |
| Application: | IF, IP, WB, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
Additional Text
Accession Number
AAH01116
Specificity
Recognizes human AK1.
Purification
Purified
Antibody Clonality
Monoclonal
A0882-65C-ML650 Datasheet
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