Catalogue Number: A1010-APE
Manufacturer: | Apexbio |
Molecular Weight: | 775.93 |
Molecular Formula: | C41H57N7O8 |
Physical state: | A solid |
Type: | Peptide |
Alias: | H2N-Leu-Val-Val-Tyr-Pro-Trp-OH |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 5 mg, 10 mg, 25 mg |
Description: Myelopeptide-2 (MP-2) (C41H57N7O8), with the sequence Leu-Val-Val-Tyr-Pro-Trp, is originally isolated from the supernatant of porcine bone marrow cell culture, and is able to restore the mitogen responsiveness of human T lymphocytes inhibited by conditioned medium from HL-60 leukemia cells or measles virus. The MP-2 recovery effect is connected with its influence on the CD3 and CD4 antigen expression on T lymphocytes. Research results also suggest that the MP-2 involvement in regulatory processes is directed to the maintenance of immune homeostasis. This peptide is perspective to be applied in antitumor and antivirus therapy. Ref:1. Mikhailova AA, Belevskaya RG, Kalyuzhnaya M, Fonina LA, Liashenko VA, Petrov RV. Myelopeptide-2 recovers interleukin-2 synthesis and interleukin-2 receptor expression in human T lymphocytes depressed by tumor products or measles virus.
Store at -20°C
Peptide used for restoring human T lymphocytes
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