UltraAvidin™- Alkaline Phosphatase
Catalogue Number: A108-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Avidin/Streptavidin Biotin Products |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 2.0 mg |
Description
Description: UltraAvidin™ is Leinco Technologies' uniquely modified form of avidin which is isolated from chicken egg whites. With a molecular weight of 60,000, there are four identical subunits each capable of binding one molecule of biotin. UltraAvidin™ from Leinco Technologies has been de-glycosylated to prevent carbohydrate moieties from adhering to lectin-like receptors on the surface of cells, thus eliminating the possibility of false positives. Unlike native avidin, UltraAvidin™ has a near neutral pI which prevents electrostatic interactions with negatively charged serum or membrane proteins. Recent studies have identified a universal recognition sequence in streptavidin which is similar to that found in several adhesion receptors.¹ Strong interactions have been shown with streptavidin and cell surface molecules. This universal recognition sequence is not present in UltraAvidin™. UltraAvidin™ may not significantly increase sensitivity in all research systems but it will assure specificity. UltraAvidin™ has been covalently conjugated to Alkaline Phosphatase from calf mucosa. The conjugate is then purified chromatographically to remove unconjugated enzyme and UltraAvidin™.
Additional Text
Concentration
1 mg/ml
Storage Note
This Alkaline Phosphatase conjugate is stable when stored at 2-8°C. Do not freeze
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