AMP Activated Protein Kinase alpha1/2 (AMPK a1/2) (MaxLight 550) (Drosophila)
Catalogue Number: A1475-01U-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9E22 (34.2) |
| Isotype: | IgG2a |
| Immunogen: | Synthetic peptide corresponding to 29aa within the N-terminal catalytic domain of Drosophila AMPK alpha. |
| Application: | IF, IP, WB, IHC, FLISA |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. AMPK is a highly conserved heterotrimeric protein kinase found in all eukaryotes. The heterotrimeric complex exists as multiple isoforms and consists of a catalytic alpha subunit, which is stabilized by non-catalytic regulatory beta- and gamma- subunits. AMPK plays a vital role in maintaining cellular energy homeostasis and is activated by rising levels of AMP under conditions of hypoxia, ischemia, exercise, low glucose levels. AMPK may play an important role in the control of type 2 diabetes and metabolic syndromes. Recent studies suggest that AMPK functions as a suppressor of cell proliferation of both malignant and normal cells.
Additional Text
Gene Name
PRKAA2
Gene ID
5563
Uniprot ID
P54646
Specificity
Recognizes both the alpha 1 and the alpha 2 isoforms of Drosophila AMP-activated protein kinase (AMPK). Species Crossreactivity: human, mouse, rat.
Purification
Protein G purified
Antibody Clonality
Monoclonal
A1475-01U-ML550 Datasheet
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