β-Amyloid (MaxLight 550)

Catalogue Number: A2275-78A-ML550-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 3H532 (DE2B4)
Isotype: IgG1
Immunogen: Synthetic peptide consisting of residues 1-17 of human amyloid beta protein. UniProt Accession: P05067
Application: IP, IHC, FLISA

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer's disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down's syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.

Additional Text

Gene Name

APP

Gene ID

351

Uniprot ID

P05067

Specificity

Recognizes the human beta amyloid peptide, which is the major protein component of the amyloid cores in neuritic plaques.

Purification

Protein A purified

Antibody Clonality

Monoclonal