Apolipoprotein F (ApoF, Lipid Transfer Inhibitor Protein, LTIP) (MaxLight 650)

Catalogue Number: A2299-76V1-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1D5
Isotype: IgG2b, kappa
Immunogen: APOF (AAH26257, 37-327aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Application: WB, IHC, FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Apolipoprotein F (Apo F), also known as lipid transfer inhibitor protein (LTIP) based on its ability to inhibit lipid transfer between lipoproteins, is a protein component of several lipoprotein classes and a physiologic regulator of cholesteryl ester transfer protein (CETP) function. Apo F activity was reported to be localized to LDL, consistent with its greater inhibitory activity on this lipoprotein.Apo F activity is controlled by its reversible incorporation into an inactive complex which provides for short-term fine-tuning of lipoprotein remodeling mediated by CETP. ApoF overexpression reduces HDL cholesterol levels by increasing clearance of HDL-CE.ApoF may be an important determinant of HDL metabolism and reverse cholesterol transport.

Additional Text

Accession Number

AAH26257

Specificity

Recognizes human APOF.

Purification

Purified

Antibody Clonality

Monoclonal