ATPase 2, Ca2+ Transporting, Sarcoplasmic Endoplasmic Reticulum (SERCA2) (MaxLight 650)
Catalogue Number: A4000-94A-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 10H15 (11D8) |
| Isotype: | IgG1, kappa |
| Immunogen: | Purified canine cardiac sarcoplasmic reticulum. |
| Application: | ICC, WB, IHC |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The sarcoplasmic reticulum of striated muscle is a specialized intracellular membrane system that plays a critical role in the contraction and relaxation of muscle. The sarco/endoplasmic reticulum Ca2+ ATPases (SERCAs) mediate Ca2+ uptake into intracellular stores. SERCA mediated Ca2+ uptake induces and maintains muscular relaxation. SERCA1 is expressed in fast-twitch muscles, whereas SERCA2 is expressed in cardiac and slow-twitch muscles. SERCA2 plays an important part in regulating cardiac contractile function.
Additional Text
Gene Name
ATP2A2
Accession Number
NP_001003214
Specificity
Recognizes human ATPase 2, Ca2+ Transporting, Sarcoplasmic Endoplasmic Reticulum.
Purification
Protein G purified
Gene ID
403878
Uniprot ID
O46674
Antibody Clonality
Monoclonal
A4000-94A-ML650 Datasheet
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