Cy5 azide
Catalogue Number: A8128-APE
| Manufacturer: | Apexbio |
| Shelf Life: | 24 months |
| Type: | Click Chemistry Reagent |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg |
Description
Description: Sulfo-Cy5 azide is a sulfonated, hydrophilic and highly water soluble dye for Click chemistry. Due to this features, the dye can be used for labeling biomolecules, especially useful for the labeling of delicate proteins and proteins prone to denaturation, purely aqueous conditions. Sulfo-Cy5 azide is not only a sulfonated but also a popular fluorophore. For labeling proteins and peptides, no organic co-solvent is needed. In life science, the sulfonate groups make the Cy dyes soluble in water and also reduce fluorescence-quenching which can arise from dye-dye interactions.In mammalian cells, Sulfo-Cy5-azide was incubated with U2OS cells. Finally, the study only find that the cells expressing tRNAIle2-5S fusion RNA can be labeled and imaged with Sulfo-Cy5-azide [1]. Reference:[1] Li, F.; Dong, J.; Hu, X.; Gong, W.; Li, J.; Shen, J.; Tian, H.; Wang, J. A Covalent Approach for Site-Specific RNA Labeling in Mammalian Cells. Angewandte Chemie International Edition, 2015, 54(15), 4597-4602.
Additional Text
Short Description
used for Click chemistry to label alkyne-modified oligonucleotides
Solubility
very high in water
Reagent:Smile String
CC1(C2=C(C=CC(=C2)S(=O)(=O)[O-])[N+](=C1C=CC=CC=C3C(C4=C(N3CCCCCC(=O)NCCCN=[N+]=[N-])C=CC(=C4)S(=O)(=O)[O-])(C)C)C)C
Storage Note
24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
A8128 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations