Cy5.5 carboxylic acid (non-sulfonated)
Catalogue Number: A8134-APE
| Manufacturer: | Apexbio |
| Shelf Life: | 24 months |
| Physical state: | A solid |
| Type: | Fluorescent Reagents |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg |
Description
Description: Cy5.5 carboxylic acid is an un-activated labeling regent which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. Cyanine 5.5 carboxylic acid instead of the drug was injected into the tumors in order to visually observe the dye release by using the in vivo imaging system (IVIS). Research show that NIR irradiation could efficiently triggered drug release from the DEPt-PEG/α-CD hydrogel in vivo [1].Reference:[1] Wang, X.; Wang, C.; Zhang, Q.; Cheng, Y. Near Infrared Light-responsive and Injectable Supramolecular Hydrogels for On-demand Drug Delivery. Chemical Communications, 2016, 52, 978-981.
Additional Text
Short Description
Non-reactive fluorophore, for control experiments, and for calibration
Reagent:Smile String
CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)C)C=CC=CC=C4C(C5=C(N4CCCCCC(=O)O)C=CC6=CC=CC=C65)(C)C)C
Solubility
insoluble in H2O; ≥16.73 mg/mL in EtOH with ultrasonic; ≥213 mg/mL in DMSO
Storage Note
24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
A8134 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations