Angiotensin II receptor (AT-1AR) Rabbit Polyclonal, affinity-purified

Catalogue Number: AB-N25AP-ATS

Manufacturer:Advanced Targeting Systems
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype:
Immunogen: Synthetic peptide corresponding to a cytoplasmic region of the receptor conjugated to keyhole limpet hemocyanin (KLH)

Description

Description: This antibody recognizes the AT-1A isoform of the Angiotensin II type 1 receptor in rat, and does not recognize isoform AT-1B or AT-2. The antisera was generated in rabbits by immunization with a synthetic peptide corresponding to a cytoplasmic region of the receptor conjugated to keyhole limpet hemocyanin (KLH). Antisera was then affinity-purified by sequential passage through two affinity columns cross-linked with the carboxy terminal sequences of the rat AT-1A and AT-1B receptors. The antisera was retained by the first, but not the second column indicating recognition of the AT-1A receptor. Adsorption of the sera was also conducted by addition of AT-1A peptide (100µg/ml) to a 1:600 dilution of the antisera.

Additional Text

Purification

Affinity Purified

Short Description

Antibody to Angiotensin II receptor (AT-1AR), affinity-purified

Usage Information

Applications include immunolabeling.

Antibody Clonality

Polyclonal