Anti-CD16/CD32 [2.4G2]

Catalogue Number: AB00123-24.1-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	Fcγ III/II Receptor; Low affinity immunoglobulin gamma Fc region receptor III; IgG Fc receptor III; Fc-gamma RIII; FcRIII; CD16; Low affinity immunoglobulin gamma Fc region receptor II; Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII IgG Fc rec
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Goat
Clone:	2.4G2
Isotype:	IgG
Immunogen:	Mouse BALB/c Macrophage J774 Cell Line.
Application:	FC, IF, IP, IHC, Blk

Overview
Datasheets

Additional Text

Gene Name

FCGR2B

Gene ID

14130

Purification

Purified

Uniprot ID

P08101, P08508

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody binds murine Fc Receptors CD16/CD32 and inhibits binding of antibodies to these. It can therefore be used as an Fc-blocking reagent, to reduce non-specific staining of cells by antibodies binding via their Fc-region. A similar effect can be achieved using the Fc Silent range of antibodies made by Absolute Antibody that prevent these interactions at the level of the Fc receptor binding site, which has been mutated to lack affinity for the Fc receptors.

Short Description

This chimeric goat antibody was made using the variable domain sequences of the original rat IgG2B format for improved compatibility with existing reagents, assays and techniques.

AB00123-24.1 Datasheet

Price

£450.00

-

Quantity
Unit Size

Find out about delivery