Anti-Beta2-Microglobulin [YTH470.5]

Catalogue Number: AB00189-10.7-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:B2M; Beta 2-micro; B2BM; β2M; β 2-micro; β2βM; CDABP0092; HDCMA22P; YTH470; YTH-470
Shipping Condition:Blue Ice
Unit(s): 500 ug
Host name: Human
Clone: YTH470.5
Isotype:
Immunogen: The original antibody was generated by fusion of the myeloma line Y3/Ag1.2.3 with spleen cells from a DA rat immunized with human cells.
Application: FC, IF, WB, Blk, Act, Ctrl (+)

Additional Text

Gene Name

B2M

Gene ID

567

Uniprot ID

P61769

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

YTH470.5 was used for IF, Activation (via complement mediated cell lysis), and WB as part of the testing performed in its original article (Bindon et al., 1988; PMID: 2973413). This antibody was also used as a positive control for blocking, as measured by FC, to analyze integrin expression on the surface of primary cultures of human airway smooth muscle cells (Freyer et al., 2001; PMID: 11713098). Furthermore, it was used as a primary monoclonal antibody in the immunocytochemistry analysis - IF, specifically - of human neuronal stem cells (Lee et al., 2005; PMID: 15607744).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.