Catalogue Number: AB00189-10.7-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | B2M; Beta 2-micro; B2BM; β2M; β 2-micro; β2βM; CDABP0092; HDCMA22P; YTH470; YTH-470 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Human |
| Clone: | YTH470.5 |
| Isotype: | |
| Immunogen: | The original antibody was generated by fusion of the myeloma line Y3/Ag1.2.3 with spleen cells from a DA rat immunized with human cells. |
| Application: | FC, IF, WB, Blk, Act, Ctrl (+) |
B2M
567
P61769
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
YTH470.5 was used for IF, Activation (via complement mediated cell lysis), and WB as part of the testing performed in its original article (Bindon et al., 1988; PMID: 2973413). This antibody was also used as a positive control for blocking, as measured by FC, to analyze integrin expression on the surface of primary cultures of human airway smooth muscle cells (Freyer et al., 2001; PMID: 11713098). Furthermore, it was used as a primary monoclonal antibody in the immunocytochemistry analysis - IF, specifically - of human neuronal stem cells (Lee et al., 2005; PMID: 15607744).
This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.