Anti-Complement Receptor 1 & 2 [7G6]

Catalogue Number: AB00236-2.0-VPB-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:CD21 & CD35
Shipping Condition:Blue Ice
Unit(s): 100 mg
Host name: Mouse
Clone: 7G6
Isotype: IgG2a
Immunogen: Purified Mouse CR1.
Application: FC, IP, WB, IHC-Fr, Blk, Stim-Co

Additional Text

Gene ID

1378

Gene Name

CR1

Antibody Clonality

Recombinant Monoclonal

Uniprot ID

P17927, P19070

Storage Note

All vivopure products are formulated in PBS only without addition of preservatives. To ensure optimal storage and prevent microbial contamination, only open and dispense under sterile conditions. Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody binds mouse complement receptors CR1 and CR2, functionally blocking CR2 leading to suppression of a normal antibody immune response (see Heyman et al. 1990, PMID: 1695671)

Short Description

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2B format, for improved compatibility with existing reagents, assays and techniques.