Anti-CD28 [JJ316]
Catalogue Number: AB00284-2.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | TP44; T-cell-specific surface glycoprotein CD28 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Mouse |
| Clone: | JJ316 |
| Isotype: | IgG2a |
| Immunogen: | Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells. |
| Application: | FC, IF, IHC, Agon, Stim-Co |
Additional Text
Gene Name
CD28
Gene ID
25660
Purification
Purified
Uniprot ID
P31042
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.
Short Description
This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB00284-2.0-BT Datasheet
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