Anti-CD28 [D665]

Catalogue Number: AB00285-2.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:TP44; T-cell-specific surface glycoprotein CD28; TP44
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Mouse
Clone: D665
Isotype: IgG2a
Immunogen: The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.
Application: FC, IHC, SPR, Agon, Stim-Co

Additional Text

Gene ID

12487

Gene Name

CD28

Uniprot ID

P31041

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).

Short Description

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.