Anti-C5 [Eculizumab]
Catalogue Number: AB00296-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Complement Component 5; CPAMD4; Complement protein C5; h5G1.1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Mouse |
| Clone: | Eculizumab |
| Isotype: | IgG1 |
| Immunogen: | C5 is activated by C5 converatse into C5a, an anaphylatoxin, and C5b a component of the membrane attack complex. |
| Application: | ELISA, EM, Blk |
Additional Text
Gene ID
727
Uniprot ID
P01031
Gene Name
C5
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody inhibits activation of C5. The human Fab version (Ab00296-10.6) of this antibody was used by Jore et al. (2016, PMID: 27018802) to determine the binding site of this antibody to C5.
Short Description
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG2/4 format, for improved compatibility with existing reagents, assays and techniques.
AB00296-1.1 Datasheet
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