Anti-Quadruplex DNA [1H6]
Catalogue Number: AB00389-24.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | G4 DNA |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Goat |
| Clone: | 1H6 |
| Isotype: | IgG |
| Immunogen: | Oxy-2 or d(TTTTGGGG)2. |
| Application: | ELISA, IF, IHC |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody binds to quadruplex DNA, which is generated through the association of four guanines bound through Hoogsteen base pairing. G4-forming sequences are associated with immunoglobulin switch regions, promoter sequences, rDNA and telomeric repeats. Ab00389-1.1 was used by Hansel-Hertsch et al. 2016 (PMID: 27618450) in immunofluorescence staining (in comparison to the BG4 anti-G quadruplex antibody, c.f. Ab00174).
Short Description
This chimeric goat antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
AB00389-24.1 Datasheet
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